🔬 Senior or Principal Scientist of Human Genetics – Shape the Future of CRM Research at Boehringer Ingelheim, Biberach an der Riß

Boehringer Ingelheim – a leading biopharmaceutical company with a legacy since 1885 – is shaping the future of medicine by investing heavily in research and development to deliver innovative therapies for high unmet medical needs. With approximately 54,500 employees across 130+ markets, the company embeds sustainability throughout its value chain and takes a long-term view on building a healthier, more sustainable world.

What You Will Drive

• Lead human-genetics support across CRM discovery and portfolio projects, leveraging population-scale biobanks, clinical cohorts, summary statistics, and longitudinal data to produce decision-grade evidence.
• Identify and prioritise genetically supported targets and indications, delivering robust genetics packages for critical portfolio milestones including Candidate Selection.
• Apply cutting-edge methodologies such as GWAS, PheWAS, fine-mapping, colocalisation, Mendelian randomisation, rare-variant analysis, polygenic risk scores, and time-to-event analysis.
• Integrate genetic evidence with molecular QTL, transcriptomic, proteomic, single-cell, and functional data to characterise causal genes, cell types, mechanisms, and disease subtypes.
• Translate findings into clear, actionable recommendations for therapeutic concept, mechanism-of-action, indication, safety, and biomarker decisions.
• Collaborate closely with CRM therapeutic area, experimental, clinical, translational, data engineering, and computational colleagues within a dynamic matrix environment.
• Lead cross-functional Human Genetics initiatives, communicate complex evidence to senior stakeholders, and build strategic external collaborations to strengthen CRM genetics data, methodologies, and shared standards.

Principal Scientist – Additional Scope

• Independently define and drive human-genetics approaches for complex CRM portfolio questions, translating strategic priorities into an integrated plan with minimal day-to-day direction.
• Own the most complex and ambiguous genetics workstreams from problem framing through portfolio decision, integrating evidence across targets, indications, mechanisms, biomarkers, and safety while managing scientific trade-offs.
• Act as a senior scientific authority in cross-functional governance and portfolio forums, influencing senior stakeholders and representing the function in high-impact collaborations.
• Set scientific quality standards, critically review genetics analyses and decision packages, and establish scalable methods, workflows, and AI-enabled approaches.
• Provide scientific leadership and coaching to Senior Scientists, defining work packages, reviewing conclusions, and supporting their growth toward greater independence.

What You Bring

• PhD in Statistical Genetics, Genetic Epidemiology, Bioinformatics, Computational Biology, Statistics, Computer Science, or a closely related field.
• Post-PhD industry experience in disease translation within a pharmaceutical or biotechnology environment.
• Strong human-genetics expertise demonstrated through successful disease translation applications and a proven track record of delivering value to drug discovery or development.
• In-depth knowledge of cardio-renal-metabolic disease biology, with experience in cardiovascular disease, kidney disease, obesity, diabetes, liver disease, or related metabolic disorders.
• Experience analysing biobank-scale and longitudinal datasets, applying statistical genetics methods to target, indication, biomarker, or patient-segmentation questions, and extensive proficiency in R or Python with reproducible analysis practices.
• Strong collaborator and communicator with proven ability to influence scientific and portfolio decisions in a matrix environment.
• Demonstrated project leadership, prioritisation, and stakeholder-management skills; proficiency with AI-assisted tools to accelerate or improve genetic analysis workflows is a plus.

Principal Scientist – Additional Requirements

• Several years of post-PhD industry experience in disease translation within pharma or biotech.
• Demonstrated ability to independently set scientific direction and prioritise across multiple complex portfolio needs, including decisions where evidence is incomplete or conflicting.
• Proven track record of leading complex, cross-functional programmes from problem framing through decision, with accountability for scientific quality, timelines, and stakeholder alignment.
• Recognised scientific authority in human genetics or a closely related field, with the credibility to challenge assumptions, resolve trade-offs, and influence senior stakeholders.
• Experience setting analytical standards, reviewing or approving work from others, and building reproducible, scalable workflows for broader team use.
• Demonstrated experience mentoring scientists and strengthening team capability through coaching, scientific review, and knowledge sharing.

Why Boehringer Ingelheim

Salary information will be shared transparently during the recruitment process, alongside a comprehensive benefits and wellbeing package. Applications from persons with severe disabilities are warmly welcomed and given preferential consideration in cases of equal qualifications. Here, your development is the priority – you will build a career in a workplace that is independent, authentic, and bold, tackling challenging work in a respectful and friendly environment where everyone is valued. Access to dedicated health and wellbeing programmes supports you along the way, while your contribution helps transform lives for generations to come.