Stellenausschreibung

The research group of Jun.-Prof. Dr. Katrin Kierdorf, Institute of Neuropathology, Faculty of Medicine, University of Freiburg offers

PhD student positions (m/f/d)

The research group is mainly interested to understand the homeostatic function and maintenance of tissue macrophage networks and is investigating the underlying processes and mechanisms. Tissue macrophages are resident immune cells and found in nearly every tissue from insects to mammals. Whereas tissue macrophages are well known to fight back infections and repair tissues, they also serve a plethora of physiological functions under steady state conditions to maintain tissue homeostasis. Primarily, our research group wants to unravel how the molecular machineries guiding unique macrophage networks are created in each organ and how these cells communicate throughout their network during homeostasis and disturbance.

We are offering two PhD position (TV-L, 65%) within a international and motivated group of researchers aiming to decipher macrophage development and biology. We are well embedded in the excellent immunological research environment in Freiburg and several collaborative research centres (e.g TRR167, TRR359, CRC1160, CRC1479) with integrated graduate schools. The positions are initially available for three years and should be filled as soon as possible. We are looking for highly motivated and ambitious candidates with a strong interest in immunology and a huge commitment to scientific research who are willing to embark on our journey to explore tissue-resident macrophages.

We are offering two very exciting and fully funded projects:

Project 1: Exploring lysosomal dysfunction in macrophages and its connection to immune-mediated pathologies, using Drosophila melanogaster and transgenic mouse models.

Project 2: Characterization of macrophage specification in adult Drosophila melanogaster and the comparison to murine tissue-resident macrophages

In both projects, we will employ two model systems, the mouse and the fruit fly, with a wide range of different techniques including flow cytometry, transcriptomics, metabolomics, histology, automated image analysis or in vivo imaging.

The candidates should hold a master’s degree in biology, biomedicine or an equivalent discipline. Experience in immunological methods or work with flies or mice is desirable.

You are interested to apply? Interested candidates should upload a CV, a strong motivation letter and at least two reference letters. Please submit your application and relevant documents using the "Apply now"-Button.

Questions? Please contact:

Tanja Wilde

tanja.wilde@uniklinik-freiburg.de

0761/270-51190

General information: Salary is assigned according to a pay scale. Unless prevented by operational or legal reasons, full-time positions are generally open to those wishing to job share. Where two candidates are equally suitable for a post, severely disabled candidates are given priority. Employment decisions are made by the Personnel Department.

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