Starte als PhD Student (m-w-d) bei Martin Luther Universität Halle Wittenberg – Dein neuer Arbeitsplatz in Halle (Saale)

External job advertisement Reg. no. 5-5815/24-D

- Korrektur -

The Martin Luther University Halle-Wittenberg, Faculty of Natural Sciences I, Institute of Pharmacy, has

a vacancy for a temporary position until 31.12.2027 at the earliest possible date as a

PhD Student (m-w-d)

to be filled as part-time (50 %).

Remuneration will be paid up to pay group E13 TV-L, depending on the tasks assigned and fulfilment of the

personal requirements.

The position is a part of a joint project between the Institute of pharmacy at MLU and computational chem-

istry group at Leibniz Institute of Plant Biochemistry (IPB-Halle). The PhD position will be placed mostly at

the computational chemistry group at IPB Halle (AG Davari).

Tasks:

• Preparation of enzyme data from public databases and transcriptomic data

• Development of machine learning (ML) architectures for the prediction of functions and enzyme-substrate

pairs

• In silico enzyme mining

• Prediction of the recombination landscape of enzyme variants by ML models

• Enzyme characterization and preparation of protein mutants

• Possibility to get a doctoral degree is given

Requirements:

• Diploma or Master's degree in computational biology, bioinformatics, cheminformatics, computational

(bio)chemistry or biophysics or a comparable field

• Profound knowledge in one of the following areas: Programming language (Python, C/C++), machine learn-

ing and deep learning methods (PyTorch, TensorFlow), knowledge management and databases, computa-

tional biochemistry or biophysics

• Experience in state-of-the-art machine learning methods (deep learning, active learning and reinforcement

learning)

• Previous experience in cheminformatics would be an advantage, but is not a prerequisite.

• Knowledge of biochemical and enzymological methods, e.g. enzyme characterization and protein muta-

tions, is an advantage

• Creative, curious, team-oriented and enthusiastic personality

Applications from severely disabled persons with equal aptitude and qualifications will be given preference.

Women are strongly encouraged to apply. Applicants with a degree that was not obtained at a German higher

education institution must submit a Statement of Comparability for Foreign Higher Education Qualifications

from the Central Office for Foreign Education (https://www.kmk.org/zab/central-office-for-for-eign-education)

as proof of equivalence.

If you have any questions, please contact Dr. Mohamed Nagia, phone: 0345 55-25952,

e-mail: mohamed.nagia@pharmazie.uni-halle.de.

Published on 16.07.2024 Page 1 / 2

Please send your application stating the reg. no. 5-5815/24-D as one PDF document with a letter of motivation,

CV, copies of diplomas and contact details of two references by 30.07.2024 to Martin Luther University Halle-

Wittenberg, Dr. Mohamed Nagia, Tel.: 0345 55-25952, E-Mail: mohamed.nagia@pharmazie.uni-halle.de.

The call for applications is subject to any budgetary restrictions.

Application costs will not be reimbursed by Martin Luther University. Application documents will only be returned

if a sufficiently stamped envelope is enclosed. An electronic application is welcome.

Published on 16.07.2024 Page 2 / 2