Stellenausschreibung

searched for the next possible date for the Department of Internal Medicin III to work at the Lab of Dr.Timon Seeger.

Within the research consortium CRC1550, the project “Disease Modeling” is designed to advance and to provide and induced pluripotent stem cell (iPSC)-based in vitro models for cardiac diseases. It is embedded in the already existing Cardio Stem Cell Hub taking advantage of established infrastructure, equipment, and standard operating procedures (SOPs). Constant integration of latest advancements in bioengineering and establishment of novel cell-based models will be a key activity of the project to facilitate modelling of cardiac diseases and to guide the development of novel targeted therapies.

Job-ID:

V000011960

Field of application:

Klinik für Kardiologie, Angiologie und Pneumologie

Location:

Heidelberg

Start date:

as of now

Job Category:

Science and teaching

Working hours:

full-time (100%)

Published:

21.11.2023

Limitation:

Temporary (2.5 years / extension is sought)

Contract:

TV-L

Your Tasks

Development of novel approaches for the functional characterization of iPSC derived cardiac cells (i.e. cardiomyocytes, endothelial cells, fibroblasts) in 2D/3D as multicellular models
Genome editing approaches for specific cardiac diseases (i.e. hypertrophic cardiomyopathy; HCM, and dilated cardiomyopathy; DCM)
Connect and interact with groups in the bioengineering department to integrate state of the art technology into iPSC based models
Engagement in managing the service project in its overlaps towards the Stem Cell Hub and supervise the technicians in all aspects of iPSC-related work
Interconnecting the various projects of the CRC regarding in-vitro based models directing specific experiments in collaboration with the respective researchers, allowing you to participate in ambitious and high-impact scientific projects, you will be strongly supported to develop your management skills and encouraged to publish on (methodological) advances in cardiac disease modeling

Your Profile

Strong background in iPSC technology
Extensive experience with culturing and differentiation of iPSC, ideally in the cardiac field, including protocol development as well as refinement and multicell based approaches
Experience in molecular methodologies (qPCR, western blot, cloning etc.) and cellular evaluation (immunostaining, transfection, etc)
Sufficient in Microsoft office applications, data analysis software (e.g. Graphpad Prism), fluent in English, strong communicative skills

We offer

Goal-oriented, individual training and development opportunities (recurrent seminars within the CRC, training courses)
Working with the latest techniques / technical equipment in regards to iPSC technology
Flexible working hours within the framework of flexitime
Possibility to publish scientifically is offered and supported
Regular team meetings
Interdisciplinary cooperation with all groups in the CRC1550
Possibility to take over project responsibility for technology development
(Partial) project management / project responsibility possible if suitable

Contact & Application

For further information please contact Dr. Timon Seeger via e-mail.

Interested?

Applications will be accepted until 15.12.2023.

Klinik für Kardiologie, Angiologie und Pneumologie
Dr. Timon Seeger
Im Neuenheimer Feld 410
69120 Heidelberg
timon.seeger@med.uni-heidelberg.de

Please note that the UKHD is subject to the provisions of the Infection Protection Act. Therefore, valid proof of measles immunity is required for all persons employed at the UKHD.

We stand for equal opportunities. Severely disabled persons are given priority in the case of equal suitability. The University Hospital aims to generally increase the proportion of women in all areas and positions in which women are underrepresented. Qualified women are therefore particularly encouraged to apply. Full-time positions are generally divisible, unless there are official or legal reasons to the

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